BDBM50039544 2-Amino-7-thiophen-3-ylmethyl-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one::CHEMBL79784
SMILES Nc1nc2c(Cc3ccsc3)c[nH]c2c(=O)[nH]1
InChI Key InChIKey=QDPMHXUWMPNTEQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50039544
Affinity DataKi: 3.5nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using 2-amino-6-mercapto-7-methyl purine ribonucleoside (MESG) as subst...More data for this Ligand-Target Pair
Affinity DataKi: 15.6nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
Affinity DataIC50: 22.6nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Rattus norvegicus)
Southern Research Institute
Curated by ChEMBL
Southern Research Institute
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Tested for its ability to inhibit calf spleen purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair