BDBM50039559 CHEMBL267803::[5-(2-Amino-6-oxo-1,6-dihydro-purin-9-yl)-pentyl]-phosphonic acid

SMILES Nc1nc2n(CCCCCP(O)(O)=O)cnc2c(=O)[nH]1

InChI Key InChIKey=ZQMIYPAADORARG-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50039559   

TargetPurine nucleoside phosphorylase(Rattus norvegicus)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50039559(CHEMBL267803 | [5-(2-Amino-6-oxo-1,6-dihydro-purin...)
Affinity DataKi:  170nMAssay Description:Tested for its ability to inhibit calf spleen purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50039559(CHEMBL267803 | [5-(2-Amino-6-oxo-1,6-dihydro-purin...)
Affinity DataKi:  170nMAssay Description:Inhibition of human erythrocytic PNP (purine nucleoside phosphorylase) in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50039559(CHEMBL267803 | [5-(2-Amino-6-oxo-1,6-dihydro-purin...)
Affinity DataKi:  500nMAssay Description:Inhibition of human HGPRTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50039559(CHEMBL267803 | [5-(2-Amino-6-oxo-1,6-dihydro-purin...)
Affinity DataKi:  1.70E+5nMAssay Description:PNP activity in human RBCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed