BDBM50040286 CHEMBL542419::trans-Allyl-(4-phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine; hydrochloride

SMILES C=CCNC1CC(c2ccccc2)c2ccccc2C1

InChI Key InChIKey=CVGHMODPNXTUCI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50040286   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50040286(CHEMBL542419 | trans-Allyl-(4-phenyl-1,2,3,4-tetra...)
Affinity DataIC50:  117nMAssay Description:Binding affinity against sigma receptor from guinea pig brain (minus cerebellum) homogenates, using the novel [3H]-(+/-)-4 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50040286(CHEMBL542419 | trans-Allyl-(4-phenyl-1,2,3,4-tetra...)
Affinity DataIC50:  117nMAssay Description:Binding affinity against sigma receptor from guinea pig brain (minus cerebellum) homogenates, using the novel [3H]-(+/-)-4 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50040286(CHEMBL542419 | trans-Allyl-(4-phenyl-1,2,3,4-tetra...)
Affinity DataIC50:  1.00E+4nMAssay Description:Binding affinity against dopamine receptor D1 from rat striatal homogenates, using [3H]SCH-23390 as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50040286(CHEMBL542419 | trans-Allyl-(4-phenyl-1,2,3,4-tetra...)
Affinity DataIC50:  6.00E+3nMAssay Description:Binding affinity against dopamine receptor D2 from rat striatal homogenates using [3H]YM-09151-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed