BDBM50040291 CHEMBL316267::Dimethyl-(1-phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine

SMILES CN(C)[C@H]1CCc2ccccc2[C@H]1c1ccccc1

InChI Key InChIKey=NLOSPVRQRDAXEJ-ZWKOTPCHSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50040291   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50040291(CHEMBL316267 | Dimethyl-(1-phenyl-1,2,3,4-tetrahyd...)
Affinity DataIC50:  954nMAssay Description:The compound was tested for affinity towards sigma-3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50040291(CHEMBL316267 | Dimethyl-(1-phenyl-1,2,3,4-tetrahyd...)
Affinity DataIC50:  2.76E+3nMAssay Description:Binding affinity against sigma receptor from guinea pig brain (minus cerebellum) homogenates, using [3H]ditolylguanidine (DTG) as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50040291(CHEMBL316267 | Dimethyl-(1-phenyl-1,2,3,4-tetrahyd...)
Affinity DataIC50:  954nMAssay Description:The compound was tested for affinity towards sigma-3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50040291(CHEMBL316267 | Dimethyl-(1-phenyl-1,2,3,4-tetrahyd...)
Affinity DataIC50:  3.34E+3nMAssay Description:Binding affinity against sigma receptor from guinea pig brain (minus cerebellum) homogenates, using [3H]ditolylguanidine (DTG) as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed