BDBM50040809 CHEMBL3353209::US9169260, 320

SMILES Cc1ccc(nc1)-n1nc(cc1NC(=O)c1cnn2cccnc12)N1CCN(CC1)C1CCC1

InChI Key InChIKey=AITFTCYSYZAHBT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50040809   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Nimbus Discovery

Curated by ChEMBL
LigandPNGBDBM50040809(CHEMBL3353209 | US9169260, 320)
Affinity DataIC50: <100nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Nimbus Discovery

Curated by ChEMBL
LigandPNGBDBM50040809(CHEMBL3353209 | US9169260, 320)
Affinity DataIC50: <100nMpH: 7.2Assay Description:The kinase activity of IRAK-4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phos...More data for this Ligand-Target Pair
In DepthDetails US Patent