BDBM50041218 3-(7-Carbamimidoyl-naphthalen-2-yl)-2-{4-[(S)-1-(1-imino-ethyl)-pyrrolidin-3-yloxy]-phenyl}-propionic acid::CHEMBL19660

SMILES CC(=N)N1CC[C@@H](C1)Oc1ccc(cc1)C(Cc1ccc2ccc(cc2c1)C(N)=N)C(O)=O

InChI Key InChIKey=AGRCGQSFFMCBRE-UXMRNZNESA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50041218   

TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041218(3-(7-Carbamimidoyl-naphthalen-2-yl)-2-{4-[(S)-1-(1...)
Affinity DataIC50:  160nMAssay Description:In vitro evaluation for the concentration needed for inhibiting factor Xa by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50041218(3-(7-Carbamimidoyl-naphthalen-2-yl)-2-{4-[(S)-1-(1...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against Coagulation factor IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50041218(3-(7-Carbamimidoyl-naphthalen-2-yl)-2-{4-[(S)-1-(1...)
Affinity DataIC50:  60nMAssay Description:Inhibitory concentration against human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50041218(3-(7-Carbamimidoyl-naphthalen-2-yl)-2-{4-[(S)-1-(1...)
Affinity DataIC50: >1.20E+6nMAssay Description:In vitro evaluation for the concentration needed for inhibiting thrombin by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed