BDBM50041419 1,2,5,8-tetrahydroxy-9,10-anthracenedione::1,2,5,8-tetrahydroxy-9,10-anthraquinone::1,2,5,8-tetrahydroxyanthra-9,10-quinone::1,2,5,8-tetrahydroxyanthracene-9,10-dione::1,2,5,8-tetrahydroxyanthraquinone::1,4,5,6-tetrahydroxyanthraquinone::Alizarinbordeaux::Alizarine Bordeaux B::CHEMBL29898::Quinalizarin, E::quinalizarin

SMILES Oc1ccc2C(=O)c3c(O)ccc(O)c3C(=O)c2c1O

InChI Key InChIKey=VBHKTXLEJZIDJF-UHFFFAOYSA-N

Data  2 KI  6 IC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50041419   

TargetCasein kinase II subunit alpha(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50041419(1,2,5,8-tetrahydroxy-9,10-anthracenedione | 1,2,5,...)
Affinity DataKi:  60nMAssay Description:Inhibition of CK2alpha (unknown origin)More data for this Ligand-Target Pair
LigandPNGBDBM50041419(1,2,5,8-tetrahydroxy-9,10-anthracenedione | 1,2,5,...)
Affinity DataKi:  5.85E+3nMAssay Description:Binding affinity to DYRK1A (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50041419(1,2,5,8-tetrahydroxy-9,10-anthracenedione | 1,2,5,...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50041419(1,2,5,8-tetrahydroxy-9,10-anthracenedione | 1,2,5,...)
Affinity DataIC50:  1.00E+3nMAssay Description:Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50041419(1,2,5,8-tetrahydroxy-9,10-anthracenedione | 1,2,5,...)
Affinity DataIC50:  110nMAssay Description:Inhibition of CK2 alpha (unknown origin) relative to controlMore data for this Ligand-Target Pair
TargetTransthyretin(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50041419(1,2,5,8-tetrahydroxy-9,10-anthracenedione | 1,2,5,...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of acid-mediated aggregation of TTR V30M mutant (unknown origin) expressed in Escherichia coli pretreated for 30 mins at pH 7 followed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM50041419(1,2,5,8-tetrahydroxy-9,10-anthracenedione | 1,2,5,...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 20 mins by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
University of Michigan

LigandPNGBDBM50041419(1,2,5,8-tetrahydroxy-9,10-anthracenedione | 1,2,5,...)
Affinity DataIC50:  4.40E+3nMpH: 7.8 T: 2°CAssay Description:Enzyme activity assay using human and murine PAI-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed