BDBM50042944 (E)-1-(2,4-Dihydroxy-phenyl)-3-(4-hydroxy-phenyl)-propenone::(E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one::1-(2,4-Dihydroxy-phenyl)-3-(4-hydroxy-phenyl)-propenone::1-(2,4-Dihydroxyphenyl)-3-(4-hydroxyphenyl)-prop-2-en-1-one::1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one::2',4',4-trihydroxychalcone::2',4,4'-trihydroxychalcone::2,4'-dihydroxy-4-hydroxychalcone::CHEMBL129795::Isoliquiritigenin (1)::cid_638278

SMILES Oc1ccc(\C=C\C(=O)c2ccc(O)cc2O)cc1

InChI Key InChIKey=DXDRHHKMWQZJHT-FPYGCLRLSA-N

Data  1 KI  38 IC50  3 EC50

PDB links: 5 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50042944   

TargetNeuraminidase(Influenza A virus)
Chosun University

Curated by ChEMBL
LigandPNGBDBM50042944((E)-1-(2,4-Dihydroxy-phenyl)-3-(4-hydroxy-phenyl)-...)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibition of oseltamivir-resistant H1N1 swine influenza virus neuraminidase H274Y mutant activity expressed in HEK293T cells after 2 hrs by spectrof...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Chosun University

Curated by ChEMBL
LigandPNGBDBM50042944((E)-1-(2,4-Dihydroxy-phenyl)-3-(4-hydroxy-phenyl)-...)
Affinity DataIC50:  3.78E+4nMAssay Description:Inhibition of Influenza A H9N2 virus neuraminidase activity after 2 hrs by spectrofluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Chosun University

Curated by ChEMBL
LigandPNGBDBM50042944((E)-1-(2,4-Dihydroxy-phenyl)-3-(4-hydroxy-phenyl)-...)
Affinity DataIC50:  4.29E+4nMAssay Description:Noncompetitive inhibition of Influenza A H1N1 virus neuraminidase activity by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Chosun University

Curated by ChEMBL
LigandPNGBDBM50042944((E)-1-(2,4-Dihydroxy-phenyl)-3-(4-hydroxy-phenyl)-...)
Affinity DataIC50:  3.27E+4nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase activity after 2 hrs by spectrofluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Chosun University

Curated by ChEMBL
LigandPNGBDBM50042944((E)-1-(2,4-Dihydroxy-phenyl)-3-(4-hydroxy-phenyl)-...)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibition of wild type H1N1 swine influenza virus neuraminidase activity expressed in HEK293T cells after 2 hrs by spectrofluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed