BDBM50043921 CHEMBL3356047::US9174993, 58

SMILES Nc1n[nH]c2nc(cnc12)-c1ccc(NS(=O)(=O)c2cc(F)ccc2F)cc1

InChI Key InChIKey=FXJISCGIBOZVFV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50043921   

TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50043921(CHEMBL3356047 | US9174993, 58)
Affinity DataIC50:  15nMAssay Description:The compounds were tested for serum and glucocorticoid-regulated kinase 1 (SGK-1) inhibitory activity in a substrate phosphorylation assay designed t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50043921(CHEMBL3356047 | US9174993, 58)
Affinity DataIC50:  730nMAssay Description:Inhibition of human SGK1 using fluo-5(6)-carboxyfluorescein)-RPRAATF-NH2 fluorescently labeled peptide by substrate phosphorylation assay in presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50043921(CHEMBL3356047 | US9174993, 58)
Affinity DataIC50:  15nMAssay Description:Inhibition of human SGK1 using fluo-5(6)-carboxyfluorescein)-RPRAATF-NH2 fluorescently labeled peptide by substrate phosphorylation assay in presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed