BDBM50045570 CHEMBL3314285

SMILES CSc1nccc(n1)-c1[nH]c(nc1-c1ccc(F)cc1)-c1ccc(O)cc1

InChI Key InChIKey=JEZWGJUZMFFAHM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50045570   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Syncom

Curated by ChEMBL
LigandPNGBDBM50045570(CHEMBL3314285)
Affinity DataIC50:  95.5nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Syncom

Curated by ChEMBL
LigandPNGBDBM50045570(CHEMBL3314285)
Affinity DataIC50:  5.96E+3nMAssay Description:Inhibition of CK1-delta (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Syncom

Curated by ChEMBL
LigandPNGBDBM50045570(CHEMBL3314285)
Affinity DataIC50:  7.83E+4nMAssay Description:Inhibition of JAK3 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Syncom

Curated by ChEMBL
LigandPNGBDBM50045570(CHEMBL3314285)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of JAK2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Syncom

Curated by ChEMBL
LigandPNGBDBM50045570(CHEMBL3314285)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of JAK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed