BDBM50045749 3-[1-(3-Hydroxy-3-phenyl-propyl)-3,4-dimethyl-piperidin-4-yl]-phenol::CHEMBL98133

SMILES C[C@H]1CN(CCC(O)c2ccccc2)CC[C@@]1(C)c1cccc(O)c1

InChI Key InChIKey=YJQIKSUIZIHGOJ-QNGGVGCWSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50045749   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045749(3-[1-(3-Hydroxy-3-phenyl-propyl)-3,4-dimethyl-pipe...)
Affinity DataKi:  0.960nMAssay Description:Binding affinity towards mu opioid receptor by displacement of [3H]-NAL from rat brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045749(3-[1-(3-Hydroxy-3-phenyl-propyl)-3,4-dimethyl-pipe...)
Affinity DataKi:  1nMAssay Description:Binding affinity towards mu-opioid receptor by the displacement of [3H]-Nal in rat brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045749(3-[1-(3-Hydroxy-3-phenyl-propyl)-3,4-dimethyl-pipe...)
Affinity DataKi:  13nMAssay Description:Binding affinity towards kappa-opioid receptor by displacement of [3H]-EKC at from guinea pig cortical tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045749(3-[1-(3-Hydroxy-3-phenyl-propyl)-3,4-dimethyl-pipe...)
Affinity DataKi:  13nMAssay Description:Binding affinity towards kappa opioid receptor by displacement of [3H]-EKC in guinea pig cortical tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed