BDBM50045758 3-[3,4-Dimethyl-1-(3-phenyl-propyl)-piperidin-4-yl]-phenol::CHEMBL320218

SMILES C[C@H]1CN(CCCc2ccccc2)CC[C@@]1(C)c1cccc(O)c1

InChI Key InChIKey=QZUYFNRMMUUWLX-PGRDOPGGSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50045758   

TargetMu-type opioid receptor(Homo sapiens (Human))
Theravance Biopharma Us

Curated by ChEMBL
LigandPNGBDBM50045758(3-[3,4-Dimethyl-1-(3-phenyl-propyl)-piperidin-4-yl...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]-DPN from recombinant human mu opioid receptor expressed in CHO-K1 cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045758(3-[3,4-Dimethyl-1-(3-phenyl-propyl)-piperidin-4-yl...)
Affinity DataKi:  0.690nMAssay Description:Binding affinity towards mu-opioid receptor by the displacement of [3H]-Nal in rat brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50045758(3-[3,4-Dimethyl-1-(3-phenyl-propyl)-piperidin-4-yl...)
Affinity DataKi:  0.690nMAssay Description:Binding affinity towards mu opioid receptor by displacement of [3H]-NAL from rat brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Theravance Biopharma Us

Curated by ChEMBL
LigandPNGBDBM50045758(3-[3,4-Dimethyl-1-(3-phenyl-propyl)-piperidin-4-yl...)
Affinity DataKi:  0.794nMAssay Description:Displacement of [3H]-DPN from guinea pig kappa opioid receptor expressed in CHO-K1 cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Theravance Biopharma Us

Curated by ChEMBL
LigandPNGBDBM50045758(3-[3,4-Dimethyl-1-(3-phenyl-propyl)-piperidin-4-yl...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]-DPN from recombinant human delta opioid receptor expressed in CHO-K1 cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Theravance Biopharma Us

Curated by ChEMBL
LigandPNGBDBM50045758(3-[3,4-Dimethyl-1-(3-phenyl-propyl)-piperidin-4-yl...)
Affinity DataKi:  15nMAssay Description:Binding affinity towards kappa-opioid receptor by displacement of [3H]-EKC at from guinea pig cortical tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Theravance Biopharma Us

Curated by ChEMBL
LigandPNGBDBM50045758(3-[3,4-Dimethyl-1-(3-phenyl-propyl)-piperidin-4-yl...)
Affinity DataKi:  15nMAssay Description:Binding affinity towards kappa opioid receptor by displacement of [3H]-EKC in guinea pig cortical tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed