BDBM50046368 CHEMBL320988::[2-[2-(1-Formyl-4-guanidino-butylcarbamoyl)-pyrrolidin-1-yl]-2-oxo-1-(3-trifluoromethyl-phenyl)-ethyl]-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)NC(C(=O)N1CCC[C@H]1C(=O)NC(CCCNC(N)=N)C=O)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=KRCPVLWZQMKRME-XBMUEBEBSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50046368   

TargetPlasminogen(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046368(CHEMBL320988 | [2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  1.50E+4nMAssay Description:Compound was tested in vitro for inhibitory activity against t-PA (tissue plasminogen activator)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046368(CHEMBL320988 | [2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046368(CHEMBL320988 | [2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  27nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046368(CHEMBL320988 | [2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  19nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046368(CHEMBL320988 | [2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity against factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed