BDBM50046949 CHEMBL3319273

SMILES Cn1ncc2cc(\C=N\c3ccc(Cl)c(Cl)c3)ccc12

InChI Key InChIKey=DHVDQXWHRNTAOC-QGMBQPNBSA-N

Data  2 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50046949   

TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM50046949(CHEMBL3319273)
Affinity DataKi:  0.460nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as decrease in H2O2 production using p-tyr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM50046949(CHEMBL3319273)
Affinity DataKi:  0.630nMAssay Description:Competitive inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells using p-tyramine as substrate by Dixon-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50046949(CHEMBL3319273)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant MAO-A expressed in baculovirus-infected insect cells using p-tyraimne substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM50046949(CHEMBL3319273)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as decrease in H2O2 production using p-tyr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM50046949(CHEMBL3319273)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as decrease in H2O2 production using p-tyr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM50046949(CHEMBL3319273)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus-infected insect cells using p-tyraimne substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50046949(CHEMBL3319273)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of rat recombinant MAO-B expressed in baculovirus-infected insect cells using p-tyraimne substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM50046949(CHEMBL3319273)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus-infected insect cells using p-tyraimne substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed