BDBM50048867 1-Benzyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-piperazine::CHEMBL54020

SMILES COc1cccc2C(CCCN3CCN(Cc4ccccc4)CC3)CCCc12

InChI Key InChIKey=UOHLLQFAMONHJJ-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50048867   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50048867(1-Benzyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]5-HT from rat hippocampal 5-hydroxytryptamine 1A receptor with 10e-6 M ketanserinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50048867(1-Benzyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  7nMAssay Description:Inhibition of [3H]DTG binding to sigma receptor from guinea pig brain cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Universit£

Curated by ChEMBL
LigandPNGBDBM50048867(1-Benzyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  26nMAssay Description:Inhibitory activity against Sigma opioid receptor type 1 isolated from whole rat membranes using [3H](+)-pentazocine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50048867(1-Benzyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  34.4nMAssay Description:Binding affinity to sigma1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50048867(1-Benzyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphth...)
Affinity DataKi:  3.89E+3nMAssay Description:Inhibitory activity against sigma receptor isolated from guinea pig brain cortex membrane using PCP as radioligand at a concentration of 10e-5 MMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed