BDBM50049061 CHEMBL3319501::US10730833, Compound 11d::US9969686, Compound 11d

SMILES Cn1cc(Cc2[nH]c3ccccc3c2C=O)c2ccccc12

InChI Key InChIKey=CMFUZBUFEXLHQF-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50049061   

TargetAryl hydrocarbon receptor(Homo sapiens (Human))
University Of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50049061(CHEMBL3319501 | US10730833, Compound 11d | US99696...)
Affinity DataEC50:  55nMAssay Description:Activation of AhR in human HepG2 cells assessed as fluorescence after 24 hrs incubation by EROD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
University Of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50049061(CHEMBL3319501 | US10730833, Compound 11d | US99696...)
Affinity DataEC50:  55nMAssay Description:This assay measures the induction of cytochrome P450-1A1 (CYP1A1), which is a major outcome of AhR activation. Whyte, J. J.; Jung, R. E.; Schmitt, C....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAryl hydrocarbon receptor(Homo sapiens (Human))
University Of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50049061(CHEMBL3319501 | US10730833, Compound 11d | US99696...)
Affinity DataEC50:  55nMAssay Description:AhR readily binds to various endogenous and xenobiotic polyaromatic heterocycles.More data for this Ligand-Target Pair
In DepthDetails US Patent