BDBM50050390 5-Methyl-6-phenylsulfanylmethyl-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL291239

SMILES Cc1c(CSc2ccccc2)cnc2nc(N)nc(N)c12

InChI Key InChIKey=PLELQCWJTXDGHD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50050390   

TargetDihydrofolate reductase(Pneumocystis carinii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50050390(5-Methyl-6-phenylsulfanylmethyl-pyrido[2,3-d]pyrim...)
Affinity DataIC50:  440nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50050390(5-Methyl-6-phenylsulfanylmethyl-pyrido[2,3-d]pyrim...)
Affinity DataIC50:  430nMAssay Description:Inhibitory activity of the compound against rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50050390(5-Methyl-6-phenylsulfanylmethyl-pyrido[2,3-d]pyrim...)
Affinity DataIC50:  34nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed