BDBM50050792 2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-phenoxy-3,3-diphenyl-propionic acid::CHEMBL66402

SMILES COc1cc(OC)nc(OC(C(O)=O)C(Oc2ccccc2)(c2ccccc2)c2ccccc2)n1

InChI Key InChIKey=FMKPVIZIITXJDD-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050792   

TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050792(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-phenoxy-3,3-...)
Affinity DataKi:  86nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50050792(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-phenoxy-3,3-...)
Affinity DataKi:  1.50E+3nMAssay Description:Binding affinity of the compound towards human Endothelin B receptor by measuring its ability to displace [125I]-ET-3 from guinea pig cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed