BDBM50051305 (3-Chloro-phenyl)-(5,6-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine::CHEMBL307209

SMILES Clc1cccc(Nc2ncnc3[nH]c(c(-c4ccccc4)c23)-c2ccccc2)c1

InChI Key InChIKey=UYXXIXVMSUKWBN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50051305   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051305((3-Chloro-phenyl)-(5,6-diphenyl-7H-pyrrolo[2,3-d]p...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of EGF-stimulated tyrosine phosphorylation in A431 cells expressing EGF-RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051305((3-Chloro-phenyl)-(5,6-diphenyl-7H-pyrrolo[2,3-d]p...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of tyrosine kinase c-SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051305((3-Chloro-phenyl)-(5,6-diphenyl-7H-pyrrolo[2,3-d]p...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of tyrosine kinase v-AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051305((3-Chloro-phenyl)-(5,6-diphenyl-7H-pyrrolo[2,3-d]p...)
Affinity DataIC50:  96nMAssay Description:In vitro inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed