BDBM50051496 CHEMBL310228::[(S)-3-(Pyrrolidine-1-carbonyl)-2-aza-bicyclo[2.2.2]oct-2-yl]-[(1R,2S)-2-(3-trifluoromethyl-phenyl)-cyclopropyl]-methanone

SMILES FC(F)(F)c1cccc(c1)[C@H]1C[C@H]1C(=O)N1C2CCC(CC2)[C@H]1C(=O)N1CCCC1

InChI Key InChIKey=NYESJNSEALKTLB-QIWRWZBJSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50051496   

TargetProlyl endopeptidase(Rattus norvegicus)
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Curated by ChEMBL
LigandPNGBDBM50051496(CHEMBL310228 | [(S)-3-(Pyrrolidine-1-carbonyl)-2-a...)
Affinity DataIC50:  3.20nMAssay Description:Inhibitory activity of the compound was evaluated against Post-proline cleaving enzyme from rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed