BDBM50053630 4-Methyl-Phenyl biguanide::CHEMBL291064::N-(4-methylphenyl)imidodicarbonimidic diamide

SMILES Cc1ccc(NC(N)=NC(N)=N)cc1

InChI Key InChIKey=ILEIGUXOYKZHRK-UHFFFAOYSA-N

Data  1 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50053630   

Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50053630(4-Methyl-Phenyl biguanide | CHEMBL291064 | N-(4-me...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for the inhibition of [3H]-GR-65,630 binding to 5-hydroxytryptamine 3 receptor expressed in NG 108-15 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50053630(4-Methyl-Phenyl biguanide | CHEMBL291064 | N-(4-me...)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at mouse TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 5(Mus musculus)
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50053630(4-Methyl-Phenyl biguanide | CHEMBL291064 | N-(4-me...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50053630(4-Methyl-Phenyl biguanide | CHEMBL291064 | N-(4-me...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human TAAR1 expressed in HEK293 cells assessed as cAMP accumulation after 20 mins by BRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed