BDBM50054564 (Z)-2-Cyano-3-cyclopropyl-N-(3-ethyl-4-trifluoromethyl-phenyl)-3-hydroxy-acrylamide::CHEMBL357459

SMILES CCc1cc(NC(=O)C(C#N)C(=O)C2CC2)ccc1C(F)(F)F

InChI Key InChIKey=XGLWOJFNZFWUOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50054564   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054564((Z)-2-Cyano-3-cyclopropyl-N-(3-ethyl-4-trifluorome...)
Affinity DataIC50:  40nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mus musculus)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50054564((Z)-2-Cyano-3-cyclopropyl-N-(3-ethyl-4-trifluorome...)
Affinity DataIC50:  71nMAssay Description:Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed