BDBM50054587 (Z)-2-Cyano-N-(4-cyano-phenyl)-3-cyclopropyl-3-hydroxy-acrylamide::Alpha-cyano-beta-hydroxy enamide, 6::CHEMBL141195
SMILES O=C(Nc1ccc(cc1)C#N)C(C#N)C(=O)C1CC1
InChI Key InChIKey=GSSLQBZZKKOMAF-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50054587
Affinity DataIC50: 600nMAssay Description:Spectrophotometric assay using crude human, recombinant DHODHase.More data for this Ligand-Target Pair
Affinity DataIC50: 7.08E+5nMAssay Description:Inhibition of Plasmodium falciparum HIs6-tagged DHODH expressed in Escherichia coli DH5alpha using L-dihydroorotate as substrate by DCIP-based spectr...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mus musculus)
Hoechst Marion Roussel
Curated by ChEMBL
Hoechst Marion Roussel
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouseMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rattus norvegicus (rat))
Hoechst Marion Roussel
Curated by ChEMBL
Hoechst Marion Roussel
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in ratMore data for this Ligand-Target Pair