BDBM50055926 CHEMBL3321938::US9884814, Compound 277

SMILES COc1ccc(CC(=O)NC(=N)N[C@H](CC(C)C)C(=O)NCc2ccc(-c3nnn[nH]3)c(F)c2)cc1OC

InChI Key InChIKey=DXLIYVPHANGHIL-LJQANCHMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50055926   

TargetCathepsin D(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM50055926(CHEMBL3321938 | US9884814, Compound 277)
Affinity DataIC50:  690nMpH: 5.5 T: 2°CAssay Description:In order to identify modulators of cathepsin D activity, a continuous enzymatic test was carried out with a synthetic peptide which carries a fluores...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin D(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM50055926(CHEMBL3321938 | US9884814, Compound 277)
Affinity DataIC50:  690nMAssay Description:Inhibition of human liver cathepsin D using MCA-labeled GKPILFFRLK(Dnp)-D-R-NH2 peptide by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed