BDBM50056392 4-Amino-5-chloro-2-methoxy-benzoic acid 2-(3,5-dimethyl-piperidin-1-yl)-ethyl ester::CHEMBL155917

SMILES COc1cc(N)c(Cl)cc1C(=O)OCCN1CC(C)CC(C)C1

InChI Key InChIKey=BUEFUOFMOXJXAR-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50056392   

Target5-hydroxytryptamine receptor 4(RAT)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50056392(4-Amino-5-chloro-2-methoxy-benzoic acid 2-(3,5-dim...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity towards 5-hydroxytryptamine 4 receptor was determined in rat striatal membranes using [3H]GR-113808 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(RAT)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50056392(4-Amino-5-chloro-2-methoxy-benzoic acid 2-(3,5-dim...)
Affinity DataKi:  2.32nMAssay Description:Binding affinity towards 5-hydroxytryptamine 4 receptor was determined in rat striatal membranes using [3H]GR-113808 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50056392(4-Amino-5-chloro-2-methoxy-benzoic acid 2-(3,5-dim...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity was measured on 5-hydroxytryptamine 3 receptor using [3H]-BRL 43694 as radioligand in rat posterior cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50056392(4-Amino-5-chloro-2-methoxy-benzoic acid 2-(3,5-dim...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity was measured on 5-hydroxytryptamine 3 receptor using [3H]-BRL 43694 as radioligand in rat posterior cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50056392(4-Amino-5-chloro-2-methoxy-benzoic acid 2-(3,5-dim...)
Affinity DataIC50:  13nMAssay Description:5-hydroxytryptamine 4 receptor antagonist activity, concentration which gave 50% reduction of the 5-HT-induced contractions in the guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed