BDBM50056399 4-Amino-5-chloro-2-methoxy-benzoic acid (R)-(1-aza-bicyclo[2.2.2]oct-3-yl) ester::CHEMBL41769
SMILES COc1cc(N)c(Cl)cc1C(=O)O[C@H]1CN2CCC1CC2
InChI Key InChIKey=HBNLYLTXNASDDE-AWEZNQCLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50056399
Affinity DataKi: 3.60nMAssay Description:Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]-BRL-43694 displacement.More data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor using [3H]-BRL-43694 in rat posterior cortexMore data for this Ligand-Target Pair
Affinity DataKi: 488nMAssay Description:Binding affinity towards 5-hydroxytryptamine 4 receptor was determined in rat striatal membranes using [3H]GR-113808 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 488nMAssay Description:Binding affinity against 5-hydroxytryptamine 4 receptor using [3H]-GR-113,808 as radioligand in rat striatumMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:5-hydroxytryptamine 4 receptor antagonist activity, concentration which gave 50% reduction of the 5-HT-induced contractions in the guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:5-hydroxytryptamine 4 receptor antagonist activity expressed as the concentration which produced a 50% reduction of 5-HT induced contraction in guine...More data for this Ligand-Target Pair
Affinity DataEC50: 110nMAssay Description:5-hydroxytryptamine 4 receptor agonist activity as increased response to electrical stimulation in guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataEC50: 110nMAssay Description:5-hydroxytryptamine 4 receptor agonist activity, concentration which gave 50% increase in the response to electrically-stimulated myenteric plexus an...More data for this Ligand-Target Pair