BDBM50056421 4-Amino-5-chloro-2-methoxy-benzoic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::CHEMBL33676

SMILES COc1cc(N)c(Cl)cc1C(=O)OC1CC2CCC(C1)N2C

InChI Key InChIKey=VDLFLQBJZNAEDS-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50056421   

Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50056421(4-Amino-5-chloro-2-methoxy-benzoic acid 8-methyl-8...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor using [3H]-BRL-43694 in rat posterior cortexMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 4(RAT)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50056421(4-Amino-5-chloro-2-methoxy-benzoic acid 8-methyl-8...)
Affinity DataKi:  64nMAssay Description:Binding affinity towards 5-hydroxytryptamine 4 receptor was determined in rat striatal membranes using [3H]GR-113808 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(RAT)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50056421(4-Amino-5-chloro-2-methoxy-benzoic acid 8-methyl-8...)
Affinity DataKi:  64.3nMAssay Description:Binding affinity against 5-hydroxytryptamine 4 receptor using [3H]-GR-113,808 as radioligand in rat striatumMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50056421(4-Amino-5-chloro-2-methoxy-benzoic acid 8-methyl-8...)
Affinity DataEC50:  27nMAssay Description:5-hydroxytryptamine 4 receptor agonist activity, concentration which gave 50% increase in the response to electrically-stimulated myenteric plexus an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50056421(4-Amino-5-chloro-2-methoxy-benzoic acid 8-methyl-8...)
Affinity DataEC50:  27nMAssay Description:5-hydroxytryptamine 4 receptor agonist activity as increased response to electrical stimulation in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails Article