BDBM50056765 CHEMBL166844::N-hydroxy-N'-[1-(4-isobutylphenyl)ethyl]urea

SMILES CC(C)Cc1ccc(cc1)C(C)NC(=O)NO

InChI Key InChIKey=VFUAHIKHBFPNJL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50056765   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056765(CHEMBL166844 | N-hydroxy-N'-[1-(4-isobutylphenyl)e...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibitory activity against 5-lipoxygenase in Human whole blood (HWBL) stimulated with calcium ionophore (A23187) and LTB4 measured by enzyme immunoa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056765(CHEMBL166844 | N-hydroxy-N'-[1-(4-isobutylphenyl)e...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibitory activity against 5-lipoxygenase catalysis (5-LO) in sonicated rat basophilic leukemia cell lysateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed