BDBM50056920 5,5'-methylenebis(2-hydroxy-3-methylbenzoic acid)::5-(3-carboxy-4-hydroxy-5-methylbenzyl)-2-hydroxy-3-methylbenzoic acid::CHEMBL113835::NSC-623548

SMILES Cc1cc(Cc2cc(C)c(O)c(c2)C(O)=O)cc(C(O)=O)c1O

InChI Key InChIKey=UPLNCYRSCVJILM-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50056920   

TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056920(5,5'-methylenebis(2-hydroxy-3-methylbenzoic acid) ...)
Affinity DataIC50:  6.18E+4nMAssay Description:Inhibitory concentration of compound against 3'-processing of HIV-1 integrase in experiment 1&2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh mobility group protein B1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50056920(5,5'-methylenebis(2-hydroxy-3-methylbenzoic acid) ...)
Affinity DataKd:  9.00E+5nMAssay Description:Binding affinity to full-length N-terminal 6His-tagged HMGB1 (unknown origin) by NMR spectraMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50056920(5,5'-methylenebis(2-hydroxy-3-methylbenzoic acid) ...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056920(5,5'-methylenebis(2-hydroxy-3-methylbenzoic acid) ...)
Affinity DataIC50:  6.85E+4nMAssay Description:Inhibitory concentration of compound against strand transfer of HIV-1 integrase in experiment 1&2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed