BDBM50059106 6-Chloro-2-(4-fluoro-phenyl)-1H-[1,8]naphthyridin-4-one::CHEMBL51729

SMILES Oc1cc(nc2ncc(Cl)cc12)-c1ccc(F)cc1

InChI Key InChIKey=UHXBIVBUQZJQAF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059106   

TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059106(6-Chloro-2-(4-fluoro-phenyl)-1H-[1,8]naphthyridin-...)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50059106(6-Chloro-2-(4-fluoro-phenyl)-1H-[1,8]naphthyridin-...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed