BDBM50059138 1-tert-Butyl-3-[2-[3-(4-methyl-piperazin-1-yl)-propylamino]-6-(2,3,5,6-tetramethyl-phenyl)-pyrido[2,3-d]pyrimidin-7-yl]-urea::CHEMBL75188

SMILES CN1CCN(CCCNc2ncc3cc(c(NC(=O)NC(C)(C)C)nc3n2)-c2c(C)c(C)cc(C)c2C)CC1

InChI Key InChIKey=XTUXOBJKZJZVKD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50059138   

TargetInsulin receptor(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50059138(1-tert-Butyl-3-[2-[3-(4-methyl-piperazin-1-yl)-pro...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of insulin receptor (InsR) tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50059138(1-tert-Butyl-3-[2-[3-(4-methyl-piperazin-1-yl)-pro...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of C-src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50059138(1-tert-Butyl-3-[2-[3-(4-methyl-piperazin-1-yl)-pro...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of Epidermal growth factor receptor (EGFr) tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed