BDBM50059588 CHEMBL3393497

SMILES CCOC(=O)c1[nH]cc2C(C3=C(CCCC3=O)Nc12)c1cccc(Oc2nc3ccccc3[nH]2)c1

InChI Key InChIKey=YXMQIWJYPNBZJS-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059588   

TargetAurora kinase A(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059588(CHEMBL3393497)
Affinity DataIC50:  17nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora A (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
TargetAurora kinase B(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059588(CHEMBL3393497)
Affinity DataIC50:  12nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed