BDBM50059595 CHEMBL3393480

SMILES CCOC(=O)c1[nH]cc2C(c3ccc(Sc4nc5cc(Cl)ccc5[nH]4)o3)C3=C(CCCC3=O)Nc12

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059595   

TargetAurora kinase A(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059595(CHEMBL3393480)
Affinity DataIC50:  34nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora A (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059595(CHEMBL3393480)
Affinity DataIC50:  10nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed