BDBM50060700 5-Oxy-7-trifluoromethyl-1,4-dihydro-pyrido[2,3-b]pyrazine-2,3-dione::CHEMBL91801

SMILES [O-][n+]1cc(cc2[n-]c(=[OH+])c(=[OH+])[n-]c12)C(F)(F)F

InChI Key InChIKey=BVTKERFASFPGRT-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50060700   

LigandPNGBDBM50060700(5-Oxy-7-trifluoromethyl-1,4-dihydro-pyrido[2,3-b]p...)
Affinity DataKi:  427nMAssay Description:In vitro binding affinity for glycine site on the NMDA receptor.More data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50060700(5-Oxy-7-trifluoromethyl-1,4-dihydro-pyrido[2,3-b]p...)
Affinity DataIC50:  1.05E+3nMAssay Description:Binding affinity in rat brain cortical membranes by the displacement of [3H]- DCKA at N-methyl-D-aspartate glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed