BDBM50061209 2-(2,4-Bis-trifluoromethyl-phenyl)-N-[(R)-2-oxo-5-phenyl-1-(2,2,2-trifluoro-ethyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-acetamide::CHEMBL16900::L-768673

SMILES FC(F)(F)CN1c2ccccc2C(=N[C@@H](NC(=O)Cc2ccc(cc2C(F)(F)F)C(F)(F)F)C1=O)c1ccccc1

InChI Key InChIKey=VVCYJFVTVHMTBV-HSZRJFAPSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50061209   

TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50061209(2-(2,4-Bis-trifluoromethyl-phenyl)-N-[(R)-2-oxo-5-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Half maximal inhibition of binding of [125I]-CCK-8 to Cholecystokinin type B receptor in guinea pig cerebral cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50061209(2-(2,4-Bis-trifluoromethyl-phenyl)-N-[(R)-2-oxo-5-...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibitory concentration against IKr potassium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50061209(2-(2,4-Bis-trifluoromethyl-phenyl)-N-[(R)-2-oxo-5-...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of Ikr current in isolated guinea pig myocytes during a 0.5 s voltage clamp step from -50 to -10 mV.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed