BDBM50062330 (R)-N*4*-Hydroxy-2-isobutyl-N*1*-((R)-1-methylcarbamoyl-2-quinolin-8-yl-ethyl)-succinamide::CHEMBL303155

SMILES CNC(=O)[C@@H](Cc1cccc2cccnc12)NC(=O)[C@H](CC(C)C)CC(=O)NO

InChI Key InChIKey=URVVMIUWONGKFU-IAGOWNOFSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062330   

TargetNeutrophil collagenase(Homo sapiens (Human))
Glycomed

Curated by ChEMBL
LigandPNGBDBM50062330((R)-N*4*-Hydroxy-2-isobutyl-N*1*-((R)-1-methylcarb...)
Affinity DataKi:  0.540nMAssay Description:The compound was tested for its binding affinity towards neutrophil collagenase (Matrix metalloproteinase-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Glycomed

Curated by ChEMBL
LigandPNGBDBM50062330((R)-N*4*-Hydroxy-2-isobutyl-N*1*-((R)-1-methylcarb...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity towards 72 kDa gelatinase (Matrix metalloproteinase-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Glycomed

Curated by ChEMBL
LigandPNGBDBM50062330((R)-N*4*-Hydroxy-2-isobutyl-N*1*-((R)-1-methylcarb...)
Affinity DataKi:  1.5nMAssay Description:The compound was tested for its binding affinity towards 92 kDa gelatinase (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed