BDBM50062522 (1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl)cyclopropanecarboxylic acid::(1S,2S)-2-[(1S)-1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]cyclopropanecarboxylic acid::(1S,2S)-2-[(S)-1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-cyclopropanecarboxylic acid::(1S,2S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-cyclopropanecarboxylic acid::(S)-2-[(S)-1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-cyclopropanecarboxylic acid::2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine::2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-cyclopropanecarboxylic acid(LY341495)::CHEMBL432038

SMILES N[C@@](CC1c2ccccc2Oc2ccccc12)([C@H]1C[C@@H]1C(O)=O)C(O)=O

InChI Key InChIKey=VLZBRVJVCCNPRJ-KPHUOKFYSA-N

Data  12 KI  25 IC50  5 EC50

PDB links: 13 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50062522   

TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50062522((1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-y...)
Affinity DataIC50:  990nMAssay Description:Antagonistic activity against metabotropic glutamate receptor 7 (mGluR7) was evaluatedMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50062522((1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-y...)
Affinity DataIC50:  16nMAssay Description:Antagonistic activity against metabotropic glutamate receptor 3 (mGluR3) was evaluatedMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50062522((1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-y...)
Affinity DataIC50:  170nMAssay Description:Antagonistic activity against metabotropic glutamate receptor 8 (mGluR8) was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50062522((1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-y...)
Affinity DataIC50:  8.20E+3nMAssay Description:Antagonistic activity against metabotropic glutamate receptor 5 (mGluR5) was evaluatedMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50062522((1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-y...)
Affinity DataIC50:  2.20E+4nMAssay Description:Antagonistic activity against metabotropic glutamate receptor 4 (mGluR4) was evaluatedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50062522((1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-y...)
Affinity DataIC50:  7.80E+3nMAssay Description:Antagonistic activity against metabotropic glutamate receptor 1 (mGluR1) was evaluatedMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50062522((1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-y...)
Affinity DataIC50:  200nMAssay Description:Antagonistic activity against metabotropic glutamate receptor 2 (mGluR2) was evaluatedMore data for this Ligand-Target Pair