BDBM50063118 3a,10-Dimethyl-7-trifluoromethyl-1,2,3a,4,5,10-hexahydro-3H-10,11b-diaza-cyclopenta[a]anthracen-9-one::CHEMBL157407

SMILES Cn1c2cc3N4CCCC4(C)CCc3cc2c(cc1=O)C(F)(F)F

InChI Key InChIKey=ORGKYZVJZBDUGT-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50063118   

TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063118(3a,10-Dimethyl-7-trifluoromethyl-1,2,3a,4,5,10-hex...)
Affinity DataKi:  78nMAssay Description:Binding affinity for human androgen receptor in transiently-transfected COS-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063118(3a,10-Dimethyl-7-trifluoromethyl-1,2,3a,4,5,10-hex...)
Affinity DataIC50:  398nMAssay Description:Antagonistic activity against human progesterone receptor B (hPR-B) in co-transfected CV-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50063118(3a,10-Dimethyl-7-trifluoromethyl-1,2,3a,4,5,10-hex...)
Affinity DataIC50:  27nMAssay Description:Antagonistic activity against human androgen receptor (hAR) in co-transfected CV-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed