BDBM50063498 CHEMBL3398501

SMILES [H][C@@]1([#6]-[#6]-[#6]-[#7]1-[#6]-[#6]\[#6]=[#6](/c1sccc1-[#6])-c1sccc1-[#6])[#6@H](-[#8])-[#6](-[#8])=O

InChI Key InChIKey=NKHZOCUHILCFHA-SJORKVTESA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50063498   

TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50063498(CHEMBL3398501)
Affinity DataKi:  66nMAssay Description:Binding affinity to human GAT1 expressed in HEK293 cells using NO71156 as unlabelled marker by LC-ESI-MS-MS based competitive MS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50063498(CHEMBL3398501)
Affinity DataKi:  102nMAssay Description:Binding affinity to mouse GAT1 expressed in HEK293 cells using NO71156 as unlabelled marker by LC-ESI-MS-MS based competitive MS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50063498(CHEMBL3398501)
Affinity DataIC50:  2.14E+3nMAssay Description:Inhibition of mouse GAT1 expressed in HEK293 cells by [3H]GABA uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(MOUSE)
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50063498(CHEMBL3398501)
Affinity DataIC50:  4.27E+4nMAssay Description:Inhibition of mouse GAT3 expressed in HEK293 cells by [3H]GABA uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Ludwig-Maximilians-Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50063498(CHEMBL3398501)
Affinity DataIC50:  724nMAssay Description:Inhibition of human GAT1 expressed in HEK293 cells by [3H]GABA uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed