BDBM50063920 (R)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-succinamide::(R)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-N4-hydroxy-2-isobutylsuccinamide::CHEMBL16520::Ro-31-9790
SMILES CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)CC(=O)NO)C(C)(C)C
InChI Key InChIKey=QRXOZHSEEGNRFC-ZYHUDNBSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50063920
Affinity DataKi: 2nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 87nMAssay Description:Inhibition of TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
Affinity DataKi: 310nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
Affinity DataIC50: 7.40nMAssay Description:Activity against Matrix metalloproteinase-2 (MMP-2).More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Activity against Matrix metalloproteinase-1 (MMP-1).More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of matrix metalloproteinase-1, Collagenase-1More data for this Ligand-Target Pair
Affinity DataIC50: 470nMAssay Description:Inhibition of matrix metalloproteinase-3, stromelysin-1More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Activity against deletion mutant of MT1-MMP lacking the transmembrane domain (deltaMT1)More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against MMP-1 (Matrix metalloproteinase-1)More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of matrix metalloproteinase-9, gelatinase-BMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human MMP1More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Activity against Matrix metalloproteinase-9 (MMP-9).More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of TNF(tumor necrosis factor) in human bloodMore data for this Ligand-Target Pair