BDBM50064474 CHEMBL3401204

SMILES Fc1ccc(cc1)N1CCc2nc(COc3ccccc3)c(Cl)n2C1=O

InChI Key InChIKey=DRXSBJILZHMYIN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50064474   

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064474(CHEMBL3401204)
Affinity DataIC50:  131nMAssay Description:Negative allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50064474(CHEMBL3401204)
Affinity DataIC50:  132nMAssay Description:Negative allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed