BDBM50064581 3-Methyl-6-{4-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-butyl}-3H-benzothiazol-2-one::CHEMBL61818

SMILES Cn1c2ccc(CCCCN3CCN(CC3)c3cccc(c3)C(F)(F)F)cc2sc1=O

InChI Key InChIKey=WZKBBAOFHGSLQZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50064581   

Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50064581(3-Methyl-6-{4-[4-(3-trifluoromethyl-phenyl)-pipera...)
Affinity DataIC50:  1.00E+3nMAssay Description:Affinity towards 5-hydroxytryptamine 1B receptor in membranes from rat frontal cortex using [3H]-5-HTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50064581(3-Methyl-6-{4-[4-(3-trifluoromethyl-phenyl)-pipera...)
Affinity DataIC50:  200nMAssay Description:Affinity towards Alpha-1A adrenergic receptor in membranes from bovine frontal cortex using [3H]-prazosinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(BOVINE)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50064581(3-Methyl-6-{4-[4-(3-trifluoromethyl-phenyl)-pipera...)
Affinity DataIC50:  400nMAssay Description:Affinity towards 5-hydroxytryptamine 2A receptor in membranes from bovine frontal cortex using [3H]-KetanserinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50064581(3-Methyl-6-{4-[4-(3-trifluoromethyl-phenyl)-pipera...)
Affinity DataIC50:  50nMAssay Description:Affinity towards Dopamine receptor D2 in membranes from bovine striatum using [3H]-racloprideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Institut De Chimie Pharmaceutique Albert Lespagnol

Curated by ChEMBL
LigandPNGBDBM50064581(3-Methyl-6-{4-[4-(3-trifluoromethyl-phenyl)-pipera...)
Affinity DataIC50:  2nMAssay Description:Affinity towards 5-hydroxytryptamine 1A receptor in membranes from bovine hippocampus using [3H]-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed