BDBM50065089 (4R,5R,6R)-Tetrahydro-1,3-bis[(3-benzamide oxime)-methyl]-5-hydroxy-4-(2-phenylethyl)-6-(phenylethyl)-2-(1H)-pyrimidinone::(4R,5R,6R)-tetrahydro-1,3-bis-](3-(N-Hydroxy-benzamidine)methyl]-5-hydroxy-4-(2-phenylethyl)-6-(phenylmethyl)-2(1H)-pyrimidinone::3-[(6-Benzyl-5-hydroxy-2-oxo-4-phenethyl-tetrahydro-pyrimidin-1-yl)bis-(methyl-N-hydroxy-benzamidine)]::3-[4-benzyl-3-(3-carbamoylbenzyl)-5-hydroxy-2-oxo-6-phenethyl-(4R,5R,6R)-hexahydro-1-pyrimidinylmethyl]N-hydroxy-benzamidine::CHEMBL284942::Tetrahydropyrimidinone derivative
SMILES ONC(=N)c1cccc(CN2[C@H](CCc3ccccc3)[C@@H](O)[C@@H](Cc3ccccc3)N(Cc3cccc(c3)C(=N)NO)C2=O)c1
InChI Key InChIKey=SMPFVGOGVVEABT-XWHIBYANSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50065089
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 0.0180nMAssay Description:Inhibitory activity against HIV proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 0.0200nMAssay Description:Inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 0.0200nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals
Curated by ChEMBL
Dupont Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 0.0200nMAssay Description:Inhibitory activity of compound against HIV-1 aspartyl protease.More data for this Ligand-Target Pair