BDBM50066333 (S)-1-((R)-2-Amino-2-cyclohexyl-acetyl)-pyrrolidine-2-carboxylic acid 5-chloro-2-cyclopropylcarbamoylmethoxy-benzylamide::CHEMBL108202
SMILES N[C@H](C1CCCCC1)C(=O)N1CCC[C@H]1C(=O)NCc1cc(Cl)ccc1OCC(=O)NC1CC1
InChI Key InChIKey=QTRLBFOGRYRBHO-NZQKXSOJSA-N
Data 7 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50066333
Affinity DataKi: 0.610nMAssay Description:Binding affinity of the compound was evaluated on serine protease thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 0.610nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+4nMAssay Description:Binding affinity of the compound was evaluated on serine protease trypsin.More data for this Ligand-Target Pair
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 3.60E+4nMAssay Description:Binding affinity of the compound was evaluated on serine protease TPA.More data for this Ligand-Target Pair
Affinity DataKi: 6.70E+4nMAssay Description:Binding affinity of the compound was evaluated on serine protease ChymotrypsinogenMore data for this Ligand-Target Pair
Affinity DataKi: 7.90E+4nMAssay Description:Binding affinity of the compound was evaluated on serine protease plasma kallikrein.More data for this Ligand-Target Pair
Affinity DataKi: 1.13E+5nMAssay Description:Binding affinity of the compound was evaluated on serine protease plasmin.More data for this Ligand-Target Pair