BDBM50066555 3-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-5-yl)-5,5-dimethyl-4,5-dihydro-isoxazole::CHEMBL421608

SMILES CC(C)(C)c1cc(cc2c1OCC2(C)C)C1=NOC(C)(C)C1

InChI Key InChIKey=RKGGTHPEGXJODP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50066555   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066555(3-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofura...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066555(3-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofura...)
Affinity DataIC50:  70nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed