BDBM50066560 (7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-5-yl)-thiophen-2-yl-methanone::CHEMBL332937

SMILES CC(C)(C)c1cc(cc2c1OCC2(C)C)C(=O)c1cccs1

InChI Key InChIKey=XLDKMNHAXYWQCC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50066560   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066560((7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-...)
Affinity DataIC50:  45nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066560((7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-...)
Affinity DataIC50:  38nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066560((7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of 5-Lipoxygenase(5-LOX)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed