BDBM50067044 (1E,4E)-1,5-Bis-(4-hydroxy-phenyl)-penta-1,4-dien-3-one::(1E,4E)-1,5-bis(4-hydroxyphenyl)penta-1,4-dien-3-one::1,5-Bis(4-hydroxyphenyl)penta-1,4-dien-3-one::1,5-Bis-(4-hydroxy-phenyl)-penta-1,4-dien-3-one::CHEMBL129134

SMILES Oc1ccc(\C=C\C(=O)\C=C\c2ccc(O)cc2)cc1

InChI Key InChIKey=FTEGUKWEUQPKIS-YDWXAUTNSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50067044   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50067044((1E,4E)-1,5-Bis-(4-hydroxy-phenyl)-penta-1,4-dien-...)
Affinity DataIC50:  4.42E+3nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]-cortisone as substrate assessed as formation of cortisol after 60 to 90 mins by radiom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50067044((1E,4E)-1,5-Bis-(4-hydroxy-phenyl)-penta-1,4-dien-...)
Affinity DataIC50:  986nMAssay Description:Inhibition of 11beta-HSD1 in Sprague-Dawley rat leydig cells at 100 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50067044((1E,4E)-1,5-Bis-(4-hydroxy-phenyl)-penta-1,4-dien-...)
Affinity DataIC50:  832nMAssay Description:Inhibition of human 11beta-HSD1 transfected in CHOP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed