BDBM50067865 CHEMBL337603::N*6*-(3,4-Dimethoxy-phenyl)-N*6*-methyl-pyrido[3,2-d]pyrimidine-2,4,6-triamine

SMILES COc1ccc(cc1OC)N(C)c1ccc2nc(N)nc(N)c2n1

InChI Key InChIKey=NEYWXHQYBGGVGI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50067865   

TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50067865(CHEMBL337603 | N*6*-(3,4-Dimethoxy-phenyl)-N*6*-me...)
Affinity DataIC50:  0.400nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50067865(CHEMBL337603 | N*6*-(3,4-Dimethoxy-phenyl)-N*6*-me...)
Affinity DataIC50:  0.880nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Toxoplasma gondiiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50067865(CHEMBL337603 | N*6*-(3,4-Dimethoxy-phenyl)-N*6*-me...)
Affinity DataIC50:  2.30nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Pneumocystis cariniiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed