BDBM50067866 CHEMBL140705::N*6*-(2-Methoxy-phenyl)-pyrido[3,2-d]pyrimidine-2,4,6-triamine

SMILES COc1ccccc1Nc1ccc2nc(N)nc(N)c2n1

InChI Key InChIKey=NYQPOZAOUVSDPK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50067866   

TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50067866(CHEMBL140705 | N*6*-(2-Methoxy-phenyl)-pyrido[3,2-...)
Affinity DataIC50:  260nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50067866(CHEMBL140705 | N*6*-(2-Methoxy-phenyl)-pyrido[3,2-...)
Affinity DataIC50:  460nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Toxoplasma gondiiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50067866(CHEMBL140705 | N*6*-(2-Methoxy-phenyl)-pyrido[3,2-...)
Affinity DataIC50:  460nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50067866(CHEMBL140705 | N*6*-(2-Methoxy-phenyl)-pyrido[3,2-...)
Affinity DataIC50:  260nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50067866(CHEMBL140705 | N*6*-(2-Methoxy-phenyl)-pyrido[3,2-...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50067866(CHEMBL140705 | N*6*-(2-Methoxy-phenyl)-pyrido[3,2-...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Pneumocystis cariniiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed