BDBM50069365 CHEMBL3330104::US9670191, F25
SMILES Cc1ccc(Cl)cc1-c1[nH]c(cc1C(N)=O)-c1ccnc(N)n1
InChI Key InChIKey=DQDASFFHMDSYAZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50069365
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant epitope-tagged JAK2 (808 to 1132) (unknown origin) using LPLDKDYYVVREPGQ as substrate by beta-countiing analysis in presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Inhibition of JAK2 V617F mutant in human SET2 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences
US Patent
Nerviano Medical Sciences
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc...More data for this Ligand-Target Pair